In the chair conformation of cyclohexane, substituents in the ____ position are generally more stable due to reduced steric interactions compared to those in the axial position.

Question

Seekh · Accepted Answer

In the chair conformation of cyclohexane, substituents in the equatorial position are generally more stable. This is because equatorial groups lie flat against the ring, so they do not clash with other atoms. Axial groups point up or down, creating 1,3‑diaxial interactions that raise steric strain. For example, a methyl group prefers the equatorial orientation because it avoids contact with the six axial hydrogens on the same side. Thus, equatorial substituents experience less steric hindrance and are energetically favored.

In the chair conformation of cyclohexane, substituents in the ____ position are generally more stable due to reduced steric interactions compared to those in the axial position.

Learning Path

Choose the Best Answer

Understanding the Answer

Key Concepts

Deep Dive: Cyclohexane Chair Conformations

Definition

Topic Definition

Ready to Master More Topics?