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Innate Immune Responses
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What underlying mechanism is primarily responsible for the increase in body temperature during a fever as a response to infection?

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Learning Path

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A

The body produces heat to directly kill pathogens

B

Immune cells release pyrogens that signal the hypothalamus to raise the body's temperature

C

Increased metabolism from the infection generates excess heat

D

The body absorbs heat from the external environment to combat the infection

Understanding the Answer

Let's break down why this is correct

Immune cells release small proteins called pyrogens. Other options are incorrect because The belief that the body simply makes heat to kill germs misses the signal step; Infection does raise metabolic activity, but the fever is not just a side effect.

Key Concepts

Innate Immune Responses
Fever Mechanism
Immune Signaling
Topic

Innate Immune Responses

Difficulty

medium level question

Cognitive Level

understand

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Definition
Definition

Innate immune responses involve natural killer cells targeting infections and tumors, inflammation causing hot, swollen areas to fight irritants, and fever as a systemic response to pathogens. Fever creates an inhospitable environment for pathogens to slow their growth. Asymptomatic infections, where pathogens multiply without causing symptoms, highlight the body's silent defense mechanisms.

Topic Definition

Innate immune responses involve natural killer cells targeting infections and tumors, inflammation causing hot, swollen areas to fight irritants, and fever as a systemic response to pathogens. Fever creates an inhospitable environment for pathogens to slow their growth. Asymptomatic infections, where pathogens multiply without causing symptoms, highlight the body's silent defense mechanisms.

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