📚 Learning Guide
Human Microbiome
hard

If an individual's gut microbiome is significantly altered due to antibiotic treatment, which of the following is the most likely underlying cause of this effect on their health?

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Choose the Best Answer

A

Reduction in microbial diversity leading to dysbiosis

B

Increased resistance to infections due to antibiotics

C

Direct damage to the intestinal lining by antibiotics

D

Enhanced production of beneficial metabolites by remaining bacteria

Understanding the Answer

Let's break down why this is correct

Answer

Antibiotics can kill many of the bacteria that normally live in the gut, leaving fewer species to compete for resources. This loss of microbial diversity means that the remaining bacteria can overgrow or allow harmful microbes to thrive, which can upset digestion and the immune system. Because the gut bacteria help train immune cells and break down food, their sudden decline can cause inflammation, diarrhea, or even infections elsewhere. For example, a person who takes broad‑spectrum antibiotics may develop a yeast overgrowth that leads to stomach discomfort and weakened immunity. Thus, the most likely underlying cause is the disruption of normal gut microbial balance, or dysbiosis, caused by the antibiotics.

Detailed Explanation

Antibiotics kill many bacteria, so the number of different species drops. Other options are incorrect because People think antibiotics make the body stronger against infections, but they mainly remove bacteria, including helpful ones; Antibiotics target bacterial cells, not human intestinal cells.

Key Concepts

Human Microbiome
Antibiotic Effects
Dysbiosis
Topic

Human Microbiome

Difficulty

hard level question

Cognitive Level

understand

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