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HomeHomework HelpbiologyTrp Operon Model

Trp Operon Model

The Trp operon model is a classic example of a repressible operon in bacteria, where the synthesis of the amino acid tryptophan is regulated by the binding of tryptophan to a repressor protein, inhibiting transcription of the operon genes when tryptophan levels are sufficient. This mechanism allows the cell to conserve resources by preventing the production of enzymes involved in tryptophan biosynthesis when it is already available.

intermediate
2 hours
Biology
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Overview

The Trp operon is a classic example of gene regulation in bacteria, specifically in Escherichia coli. It consists of genes responsible for synthesizing tryptophan, an essential amino acid. The operon is regulated by a repressor protein that binds to the operator region when tryptophan is abundant, p...

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Key Terms

Operon
A cluster of genes under the control of a single promoter.

Example: The lac operon in E. coli regulates lactose metabolism.

Repressor
A protein that inhibits gene expression by binding to the operator.

Example: The Trp repressor binds to the operator when tryptophan is present.

Corepressor
A small molecule that cooperates with a repressor to turn off gene transcription.

Example: Tryptophan acts as a corepressor for the Trp operon.

Promoter
A DNA sequence where RNA polymerase binds to initiate transcription.

Example: The Trp operon has a specific promoter for gene transcription.

Operator
A segment of DNA where the repressor binds to block transcription.

Example: The operator of the Trp operon is where the repressor attaches.

Transcription
The process of copying a segment of DNA into RNA.

Example: Transcription of the Trp operon produces mRNA for tryptophan synthesis.

Related Topics

Lac Operon
A model for understanding gene regulation in bacteria, focusing on lactose metabolism.
intermediate
Gene Regulation
The mechanisms that control the expression of genes in organisms.
intermediate
Metabolic Pathways
Series of chemical reactions in a cell that lead to the synthesis or breakdown of substances.
advanced

Key Concepts

operon structuregene regulationrepression mechanismtryptophan synthesis