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HomeHomework HelpbiologySemiconservative Replication

Semiconservative Replication

Semiconservative replication, as demonstrated by the Meselson-Stahl experiment, is the process by which DNA is duplicated in such a way that each new double helix consists of one original (parental) strand and one newly synthesized strand, ensuring that genetic information is accurately passed on during cell division.

intermediate
2 hours
Biology
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Overview

Semiconservative replication is a fundamental biological process that ensures the accurate duplication of DNA during cell division. This method of replication was confirmed by the Meselson-Stahl experiment, which demonstrated that each new DNA molecule consists of one original strand and one newly s...

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Key Terms

DNA
Deoxyribonucleic acid, the molecule that carries genetic information.

Example: DNA is found in the nucleus of cells.

Nucleotide
The basic building block of DNA, consisting of a sugar, phosphate, and a nitrogenous base.

Example: A nucleotide can be adenine, thymine, cytosine, or guanine.

Helicase
An enzyme that unwinds the DNA double helix during replication.

Example: Helicase separates the two strands of DNA.

DNA Polymerase
An enzyme that synthesizes new DNA strands by adding nucleotides.

Example: DNA polymerase is essential for DNA replication.

Centrifugation
A technique used to separate mixtures based on density by spinning them at high speeds.

Example: Centrifugation was used in the Meselson-Stahl experiment.

Isotope
Atoms of the same element with different numbers of neutrons.

Example: Heavy nitrogen is an isotope used in DNA studies.

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Key Concepts

DNA structureReplication processMeselson-Stahl experimentBase pairing