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HomeHomework HelpbiologyProphase in Mitosis

Prophase in Mitosis

Prophase is the first stage of mitosis, during which chromatin condenses into visible chromosomes, each consisting of two sister chromatids joined at the centromere. Additionally, the nuclear envelope begins to break down, and the mitotic spindle starts to form, facilitating chromosome movement.

beginner
1 hour
Biology
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Overview

Prophase is a critical phase in the process of mitosis, marking the beginning of cell division. During this stage, chromatin condenses into distinct chromosomes, making them visible under a microscope. The nuclear envelope starts to break down, allowing the spindle apparatus to form and prepare for ...

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Key Terms

Chromatin
A complex of DNA and proteins found in the nucleus, which condenses to form chromosomes during cell division.

Example: Chromatin is less visible during interphase but becomes tightly packed during prophase.

Chromosome
A structure made of DNA and proteins that carries genetic information.

Example: Humans have 46 chromosomes, which are visible during prophase.

Nuclear Envelope
A double membrane that surrounds the nucleus, separating it from the cytoplasm.

Example: The nuclear envelope breaks down during prophase to allow spindle fibers to access chromosomes.

Spindle Apparatus
A structure made of microtubules that helps separate chromosomes during mitosis.

Example: The spindle apparatus forms during prophase and is crucial for chromosome movement.

Centrosome
An organelle that serves as the main microtubule organizing center and is involved in cell division.

Example: Centrosomes move to opposite poles of the cell during prophase.

Sister Chromatids
Identical copies of a chromosome connected by a centromere.

Example: Each chromosome consists of two sister chromatids during prophase.

Related Topics

Metaphase
The stage following prophase where chromosomes align at the cell's equator.
intermediate
Anaphase
The stage where sister chromatids are pulled apart to opposite poles of the cell.
intermediate
Telophase
The final stage of mitosis where chromosomes de-condense and the nuclear envelope re-forms.
intermediate
Cytokinesis
The process that follows mitosis, resulting in the division of the cytoplasm and formation of two daughter cells.
intermediate

Key Concepts

Chromosome condensationNuclear envelope breakdownSpindle formationCentrosome movement