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HomeHomework HelpbiologyNondisjunction Disorders

Nondisjunction Disorders

Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division, leading to an abnormal distribution of chromosomes in daughter cells. This can result in chromosomal disorders, which are genetic conditions caused by an atypical number of chromosomes, such as Down syndrome or Turner syndrome.

intermediate
3 hours
Biology
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Overview

Nondisjunction is a critical concept in genetics that refers to the failure of chromosomes to separate properly during cell division. This can lead to various chromosomal disorders, such as Down syndrome, Turner syndrome, and Klinefelter syndrome. Understanding nondisjunction is essential for recogn...

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Key Terms

Chromosome
A structure made of DNA and proteins that contains genetic information.

Example: Humans have 46 chromosomes in each cell.

Meiosis
A type of cell division that reduces the chromosome number by half, producing gametes.

Example: Meiosis produces sperm and egg cells.

Trisomy
A condition where an individual has three copies of a chromosome instead of two.

Example: Down syndrome is caused by trisomy of chromosome 21.

Monosomy
A condition where an individual has only one copy of a chromosome instead of two.

Example: Turner syndrome is caused by monosomy of the X chromosome.

Genetic Counseling
A process to help individuals understand genetic conditions and their implications.

Example: Genetic counseling is often recommended for families with a history of chromosomal disorders.

Amniocentesis
A medical procedure used to obtain amniotic fluid for genetic testing.

Example: Amniocentesis can detect chromosomal disorders in a fetus.

Related Topics

Genetic Mutations
Study of changes in DNA that can lead to genetic disorders.
intermediate
Chromosomal Abnormalities
Exploration of various types of chromosomal abnormalities and their effects.
intermediate
Prenatal Genetics
Understanding genetic testing and screening methods during pregnancy.
intermediate

Key Concepts

ChromosomeMeiosisTrisomyMonosomy