Overview
G-protein coupled receptors (GPCRs) are essential components of cellular communication, acting as gateways for signals from the external environment. They play a critical role in various physiological processes, including sensory perception, immune responses, and neurotransmission. Understanding GPC...
Key Terms
Example: Hormones are ligands that bind to GPCRs.
Example: GPCRs have transmembrane domains that interact with the cell's exterior.
Example: G-proteins are activated by GPCRs upon ligand binding.
Example: cAMP is a common second messenger activated by GPCRs.
Example: One activated GPCR can activate multiple G-proteins.
Example: GPCRs are major targets in pharmacology for drug development.
Related Topics
Signal Transduction Pathways
Study the various pathways through which signals are transmitted in cells.
intermediatePharmacology of Receptors
Explore how different receptors, including GPCRs, are targeted in drug therapy.
advancedCellular Communication
Learn about the different methods cells use to communicate with each other.
intermediateKey Concepts
Signal TransductionLigand BindingG-ProteinsCellular Response