Overview
Frameshift mutations are significant genetic changes that occur when nucleotides are added or removed from a DNA sequence, shifting the reading frame of the genetic code. This alteration can lead to the production of entirely different proteins, which may disrupt normal biological functions and resu...
Key Terms
Example: A mutation in the BRCA1 gene can increase the risk of breast cancer.
Example: A nucleotide can be adenine, thymine, cytosine, or guanine.
Example: A shift in the reading frame can change the entire protein produced.
Example: An insertion can lead to a frameshift mutation.
Example: A deletion can also cause a frameshift mutation.
Example: Protein synthesis involves transcription and translation.
Related Topics
Point Mutations
Point mutations involve a change in a single nucleotide and can lead to different effects than frameshift mutations.
intermediateGenetic Engineering Techniques
Explore methods used to modify genes, including how frameshift mutations can be corrected.
advancedMolecular Biology Techniques
Learn about techniques used to study DNA and mutations, including sequencing and PCR.
intermediateKey Concepts
DNA structureMutation typesProtein synthesisGenetic disorders