Overview
Cyclins and cyclin-dependent kinases (CDKs) are essential components of the cell cycle, which is the process by which cells grow and divide. Cyclins are proteins that regulate the timing of the cell cycle, while CDKs are enzymes that, when activated by cyclins, phosphorylate target proteins to promo...
Key Terms
Example: Cyclin D is important for the transition from G1 to S phase.
Example: CDK2 is activated by cyclin E to promote DNA synthesis.
Example: The cell cycle includes G1, S, G2, and M phases.
Example: CDKs phosphorylate target proteins to initiate cell cycle progression.
Example: The G1 checkpoint checks for DNA damage before entering S phase.
Example: Mutations in cyclin genes can lead to uncontrolled cell division.
Related Topics
Key Concepts
Cell Cycle RegulationProtein InteractionsPhases of Cell CycleCancer Biology