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HomeHomework HelpbiologyChargaff's Rules

Chargaff's Rules

Chargaff's rules state that in a double-stranded DNA molecule, the amount of adenine (A) is equal to thymine (T), and the amount of cytosine (C) is equal to guanine (G), reflecting specific base pairing relationships that are crucial for the structure and function of DNA.

intermediate
2 hours
Biology
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Overview

Chargaff's rules are fundamental principles in molecular biology that describe the specific pairing of nitrogenous bases in DNA. These rules state that adenine (A) pairs with thymine (T) and cytosine (C) pairs with guanine (G), ensuring the stability and integrity of the DNA structure. Chargaff's ob...

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Key Terms

Adenine
A nitrogenous base that pairs with thymine in DNA.

Example: Adenine is one of the four bases in DNA.

Thymine
A nitrogenous base that pairs with adenine in DNA.

Example: Thymine complements adenine in the DNA structure.

Cytosine
A nitrogenous base that pairs with guanine in DNA.

Example: Cytosine is essential for the stability of DNA.

Guanine
A nitrogenous base that pairs with cytosine in DNA.

Example: Guanine forms a base pair with cytosine.

Nucleotide
The basic building block of DNA, consisting of a sugar, phosphate, and a base.

Example: Each nucleotide in DNA contains one of the four bases.

DNA Replication
The process by which DNA makes a copy of itself.

Example: Chargaff's rules ensure accurate DNA replication.

Related Topics

DNA Structure
Study the double helix structure of DNA and its components.
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Genetic Engineering
Explore techniques used to manipulate DNA for various applications.
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Molecular Biology
Learn about the molecular mechanisms of biological processes.
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Key Concepts

Base PairingDNA StructureNucleotide CompositionGenetic Information