Definition
RNA interference (RNAi) is a cellular mechanism that regulates gene expression through small RNA molecules, such as small interfering RNA (siRNA) and microRNA (miRNA), which bind to complementary messenger RNA (mRNA) sequences, leading to mRNA degradation or inhibition of translation. This process plays a crucial role in controlling gene activity and maintaining cellular homeostasis.
Summary
RNA interference (RNAi) is a vital cellular process that regulates gene expression through small RNA molecules, specifically siRNA and miRNA. siRNA primarily degrades target mRNA, while miRNA inhibits translation, both contributing to gene silencing. This mechanism is crucial for maintaining cellular functions and protecting against viral infections. In recent years, RNAi has gained significant attention for its potential applications in medicine, particularly in gene therapy and cancer treatment. By harnessing the power of RNAi, researchers aim to develop targeted therapies that can effectively silence harmful genes, offering new hope for treating various diseases. Understanding RNAi is essential for advancing genetic research and therapeutic strategies.
Key Takeaways
Role of RNAi
RNA interference is essential for regulating gene expression and protecting cells from viruses.
highsiRNA vs miRNA
siRNA is typically involved in the degradation of mRNA, while miRNA regulates gene expression by inhibiting translation.
mediumApplications in Medicine
RNAi technology has potential applications in treating diseases like cancer and genetic disorders.
highMechanism of Action
Understanding how RNAi works helps in developing targeted therapies and improving gene regulation.
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