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HomeHomework HelpgenomicsWhole-Genome Shotgun Sequencing

Whole-Genome Shotgun Sequencing

Whole-genome shotgun metagenomic sequencing is a technique that involves sequencing all DNA present in a microbial sample. This approach provides a comprehensive view of the genetic content of a microbial community, allowing for the identification of species and functional analysis.

intermediate
5 hours
Genomics
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Overview

Whole-genome shotgun metagenomic sequencing is a powerful technique that allows researchers to analyze the genetic material from diverse microbial communities in various environments. By using this method, scientists can gain insights into the roles and interactions of microorganisms, which are cruc...

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Key Terms

Metagenomics
The study of genetic material recovered directly from environmental samples.

Example: Metagenomics helps identify microbial diversity in soil.

Shotgun Sequencing
A method of sequencing DNA by randomly breaking it into small fragments and sequencing those fragments.

Example: Shotgun sequencing is used to sequence complex genomes.

Bioinformatics
The application of computer technology to manage biological information.

Example: Bioinformatics tools are essential for analyzing sequencing data.

DNA Extraction
The process of isolating DNA from cells or tissues.

Example: DNA extraction is the first step in sequencing.

Sequencing
Determining the order of nucleotides in a DNA molecule.

Example: Sequencing reveals the genetic code of an organism.

Ecosystem
A biological community of interacting organisms and their physical environment.

Example: The rainforest is a diverse ecosystem.

Related Topics

Next-Generation Sequencing
Explores advanced sequencing technologies that allow for faster and cheaper genome sequencing.
intermediate
Environmental Genomics
Focuses on the genetic analysis of environmental samples to understand ecosystem functions.
intermediate
Microbial Ecology
Studies the interactions and relationships of microorganisms within their environments.
intermediate

Key Concepts

MetagenomicsShotgun SequencingDNA ExtractionBioinformatics