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HomeHomework HelpgeneticsPleiotropy Explained

Pleiotropy Explained

Pleiotropy is a genetic phenomenon where a single gene affects multiple, seemingly unrelated phenotypic traits. This occurs because the gene product can participate in various biological pathways or processes, influencing different characteristics simultaneously.

intermediate
2 hours
Genetics
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Overview

Pleiotropy is a fascinating genetic phenomenon where a single gene can influence multiple traits in an organism. This complexity highlights the interconnectedness of genetic traits and their expressions. For instance, a mutation in a single gene can lead to various health issues or physical characte...

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Key Terms

Gene
A segment of DNA that contains instructions for building proteins.

Example: The gene for eye color determines the pigment in the iris.

Phenotype
The observable traits of an organism resulting from the interaction of its genotype and environment.

Example: Height, eye color, and blood type are phenotypes.

Genotype
The genetic makeup of an organism, representing the alleles it carries.

Example: A person may have a genotype of Bb for eye color.

Dominant Trait
A trait that is expressed when at least one dominant allele is present.

Example: Brown eyes are often a dominant trait over blue eyes.

Recessive Trait
A trait that is only expressed when two recessive alleles are present.

Example: Blue eyes are a recessive trait.

Sickle Cell Anemia
A genetic disorder caused by a mutation in the hemoglobin gene, leading to misshaped red blood cells.

Example: Individuals with sickle cell anemia may experience pain and fatigue.

Related Topics

Epistasis
The interaction between genes where one gene can mask the effect of another.
intermediate
Polygenic Inheritance
A trait controlled by multiple genes, leading to a range of phenotypes.
intermediate
Genetic Disorders
Conditions caused by abnormalities in genes or chromosomes.
advanced

Key Concepts

Gene FunctionMultiple TraitsGenetic VariationPhenotype