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HomeHomework HelpchemistryFischer Projection and Chirality

Fischer Projection and Chirality

A method of representing chiral molecules in two dimensions and the property of a molecule that makes it non-superposable on its mirror image, including the concept of asymmetric carbon atoms, stereogenic centers, and enantiomers

intermediate
2 hours
Chemistry
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Overview

Fischer projections are a vital tool in organic chemistry for representing chiral molecules in a two-dimensional format. Understanding chirality is essential as it influences how molecules interact in biological systems, affecting drug efficacy and material properties. By mastering Fischer projectio...

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Key Terms

Chirality
A property of a molecule that makes it non-superimposable on its mirror image.

Example: The left and right hands are chiral; they cannot be perfectly aligned.

Fischer Projection
A two-dimensional representation of a three-dimensional organic molecule.

Example: The Fischer projection of glucose shows its chiral centers.

Chiral Center
A carbon atom bonded to four different groups, leading to chirality.

Example: Lactic acid has one chiral center.

Stereochemistry
The study of the spatial arrangement of atoms in molecules.

Example: Stereochemistry helps explain the different properties of enantiomers.

Enantiomers
Pairs of molecules that are mirror images of each other.

Example: Thalidomide exists as two enantiomers with different effects.

Isomer
Compounds with the same molecular formula but different structures.

Example: Butane and isobutane are structural isomers.

Related Topics

Stereoisomerism
The study of isomers that differ in the spatial arrangement of atoms.
intermediate
Chiral Drugs
Exploration of how chirality affects drug design and efficacy.
advanced
Molecular Geometry
Understanding the three-dimensional arrangement of atoms in molecules.
intermediate

Key Concepts

ChiralityFischer ProjectionStereochemistryChiral Centers