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HomeHomework HelpbiologyTranscriptional Regulation

Transcriptional Regulation

Processes by which gene expression is controlled at the transcription level through activators and repressors.

intermediate
3 hours
Biology
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Overview

Transcriptional regulation is a fundamental process that controls gene expression, allowing cells to respond to their environment and differentiate into various cell types. It involves various mechanisms, including the action of transcription factors, enhancers, and silencers, which work together to...

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Key Terms

Gene Expression
The process by which information from a gene is used to synthesize a functional gene product.

Example: The expression of the insulin gene is crucial for glucose metabolism.

Transcription Factor
Proteins that help regulate the transcription of specific genes by binding to nearby DNA.

Example: The transcription factor NF-kB is involved in immune response.

Enhancer
A DNA sequence that increases the likelihood of transcription of a particular gene.

Example: Enhancers can be located far from the gene they regulate.

Silencer
A DNA sequence that can repress the transcription of a gene.

Example: Silencers help control the timing of gene expression.

RNA Processing
The modification of RNA before it is translated into a protein.

Example: Splicing removes introns from pre-mRNA.

mRNA Stability
The lifespan of mRNA molecules in the cell, affecting how much protein is produced.

Example: Stable mRNA leads to higher protein synthesis.

Related Topics

Epigenetics
The study of changes in gene expression that do not involve alterations to the underlying DNA sequence.
advanced
Gene Therapy
A technique that modifies a person's genes to treat or prevent disease.
advanced
Molecular Biology Techniques
Methods used to study the molecular mechanisms of biological processes.
intermediate

Key Concepts

Gene ExpressionTranscription FactorsEnhancersSilencers