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HomeHomework HelpbiologySecond Messengers

Second Messengers

Second messengers are intracellular signaling molecules, such as cyclic adenosine monophosphate (cAMP) and calcium ions (Ca²⁺), that relay and amplify signals from cell surface receptors to target molecules within the cell, facilitating various physiological responses. They play a crucial role in signal transduction pathways, enabling cells to respond to external stimuli.

intermediate
2 hours
Biology
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Overview

Second messengers, such as cAMP and calcium ions, are crucial for cellular communication. They help transmit signals from the cell surface to internal targets, enabling cells to respond to various stimuli. Understanding these molecules is essential for grasping how cells function and interact with t...

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Key Terms

Second Messenger
A molecule that transmits signals inside a cell after the binding of a signaling molecule to a receptor.

Example: cAMP and Ca2+ are common second messengers.

cAMP
Cyclic adenosine monophosphate, a second messenger involved in many biological processes.

Example: cAMP activates protein kinase A.

Calcium Ions (Ca2+)
A vital second messenger that regulates various cellular functions.

Example: Ca2+ release triggers muscle contraction.

Signal Transduction
The process by which a cell responds to external signals through a series of molecular events.

Example: Hormones binding to receptors initiate signal transduction.

Receptor
A protein on the cell surface that binds to signaling molecules.

Example: Insulin receptors bind insulin to regulate glucose levels.

Protein Kinase
An enzyme that modifies other proteins by adding phosphate groups.

Example: Protein kinase A is activated by cAMP.

Related Topics

Hormonal Signaling
Explores how hormones act as signaling molecules and their effects on target cells.
intermediate
Neurotransmission
Examines how signals are transmitted in the nervous system, including the role of second messengers.
advanced
Cellular Metabolism
Focuses on how signaling pathways regulate metabolic processes in cells.
intermediate

Key Concepts

cAMPCalcium Ions (Ca2+)Signal TransductionCellular Response