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HomeHomework HelpbiologyRough Endoplasmic Reticulum

Rough Endoplasmic Reticulum

The rough endoplasmic reticulum (RER) is a membranous organelle characterized by ribosomes attached to its cytoplasmic surface, which facilitates the synthesis and processing of proteins destined for secretion or for use within the cell. It plays a crucial role in the folding, modification, and transport of these proteins to other cellular compartments.

intermediate
2 hours
Biology
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Overview

The Rough Endoplasmic Reticulum (RER) is a vital organelle in eukaryotic cells, primarily responsible for the synthesis and processing of proteins. Its rough appearance is due to the ribosomes attached to its surface, which play a crucial role in translating messenger RNA into polypeptides. Once syn...

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Key Terms

Endoplasmic Reticulum
A network of membranes within the cell that helps in the synthesis and transport of proteins and lipids.

Example: The endoplasmic reticulum is divided into rough and smooth types.

Ribosome
A molecular machine that synthesizes proteins by translating messenger RNA.

Example: Ribosomes can be found free in the cytoplasm or attached to the RER.

Protein Folding
The process by which a protein assumes its functional shape or conformation.

Example: Proper protein folding is essential for the protein's function.

Post-Translational Modification
Chemical changes to a protein after it has been synthesized, affecting its function.

Example: Glycosylation is a common post-translational modification.

Golgi Apparatus
An organelle that modifies, sorts, and packages proteins for secretion or delivery to other organelles.

Example: Proteins from the RER are sent to the Golgi apparatus for further processing.

Cytoplasm
The jelly-like substance within a cell that contains organelles.

Example: Ribosomes float freely in the cytoplasm or are attached to the RER.

Related Topics

Smooth Endoplasmic Reticulum
The Smooth Endoplasmic Reticulum is involved in lipid synthesis and detoxification processes.
intermediate
Protein Folding Diseases
Conditions caused by misfolded proteins, highlighting the importance of proper protein folding.
advanced
Cell Membrane Structure
Understanding the composition and function of cell membranes, including the role of proteins.
intermediate

Key Concepts

Protein SynthesisRibosomesCellular OrganellesMembrane Structure