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HomeHomework HelpbiologyExtracellular Matrix

Extracellular Matrix

The extracellular matrix (ECM) is a complex network of proteins and carbohydrates secreted by cells that provides structural and biochemical support to surrounding cells, influencing their behavior and function. It plays a critical role in tissue development, maintenance, and repair.

intermediate
2 hours
Biology
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Overview

The extracellular matrix (ECM) is a vital component of tissues, providing structural support and facilitating communication between cells. It is composed of various proteins and carbohydrates, each playing specific roles in maintaining tissue integrity and function. Understanding the ECM is crucial ...

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Key Terms

Collagen
A primary structural protein in the ECM that provides strength.

Example: Collagen fibers are abundant in tendons.

Elastin
A protein that allows tissues to resume their shape after stretching.

Example: Elastin is found in skin and blood vessels.

Proteoglycans
Molecules consisting of a core protein and glycosaminoglycan chains that help retain water.

Example: Proteoglycans are important for cartilage structure.

Fibronectin
A glycoprotein that helps cells attach to the ECM.

Example: Fibronectin is involved in wound healing.

Glycosaminoglycans
Long unbranched polysaccharides that are part of the ECM.

Example: Hyaluronic acid is a type of glycosaminoglycan.

Tissue Engineering
The use of a combination of cells, engineering, and materials methods to improve or replace biological tissues.

Example: Tissue engineering can create skin grafts.

Related Topics

Cell Signaling
The process by which cells communicate with each other, often influenced by the ECM.
intermediate
Tissue Repair
The mechanisms by which tissues heal and regenerate, involving the ECM.
intermediate
Cancer Biology
The study of cancer development, including the role of the ECM in tumor progression.
advanced

Key Concepts

StructureFunctionComponentsRole in Tissue