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HomeHomework HelpbiochemistryFeedback Inhibition of Enzymes

Feedback Inhibition of Enzymes

Feedback inhibition of enzymes is a regulatory mechanism in which the end product of a metabolic pathway inhibits an enzyme involved in its synthesis, thereby preventing overproduction and maintaining homeostasis within the cell. This process typically occurs through non-competitive inhibition, where the end product binds to an allosteric site on the enzyme, altering its activity.

intermediate
2 hours
Biochemistry
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Overview

Feedback inhibition is a vital regulatory mechanism in biochemistry that helps maintain balance within metabolic pathways. By inhibiting the activity of enzymes involved in the production of end products, cells can prevent the overproduction of substances, ensuring that resources are used efficientl...

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Key Terms

Enzyme
A protein that accelerates chemical reactions in the body.

Example: Amylase helps break down starch into sugars.

Metabolic Pathway
A series of chemical reactions occurring within a cell.

Example: Glycolysis is a metabolic pathway that converts glucose into pyruvate.

Substrate
The reactant molecule upon which an enzyme acts.

Example: Lactose is the substrate for the enzyme lactase.

Product
The end result of a chemical reaction.

Example: Glucose is a product of the breakdown of starch.

Negative Feedback
A process that counteracts changes in a system to maintain stability.

Example: In temperature regulation, sweating cools the body down.

Allosteric Site
A site on an enzyme where molecules can bind and affect enzyme activity.

Example: Binding of a regulatory molecule at the allosteric site can enhance or inhibit enzyme function.

Related Topics

Enzyme Kinetics
Study of the rates of enzyme-catalyzed reactions and factors affecting them.
intermediate
Metabolic Regulation
Understanding how metabolic pathways are controlled and regulated.
intermediate
Biochemical Pathways
Exploration of complex networks of biochemical reactions in living organisms.
advanced

Key Concepts

enzyme regulationmetabolic pathwaysnegative feedbackhomeostasis